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(1) Zattra E, Coleman C, Arad S, et al. Polypodium leucotomos extract decreases UV-induced Cox-2 expression and inflammation, enhances DNA repair, and decreases mutagenesis in hairless mice. Am J Pathol. 2009;175:1952–1961.

(2) Middelkamp-Hup MA, Pathak MA, Parrado C, et al. Oral Polypodium leucotomos extract decreases ultraviolet-induced damage of human skin. J Am Acad Dermatol. 2004;51:910918.

(3) Gonzalez S, Pathak MA. Inhibition of ultraviolet-induced formation of reactive oxygen species, lipid peroxidation, erythema and skin photosensitization by Polypodium Leucotomos. Photodermatol Photoimmunol Photomed 1996;12:45-56.

(4) Brieva A, Guerrero A, Pivel JP. Immunomodulatory properties of a hydrophilic extract of Polypodium leucotomos. Inflammopharmacol 2002;9:361-71.

(5) Alcaraz MV, Pathak MA, Rius F, Kollias N, Gonzalez S. An extract of Polypodium leucotomos appears to minimize certain photoaging changes in a hairless albino mouse animal model: a pilot study. Photodermatol Photoimmunol Photomed 1999;15:120-6.

(6) Martin LK, Caperton C, Woolery-Lloyd H, Avashia N. (2012).

(7) Mulero M, Rodrı´guez-Yanes E, Nogue´s MR, Giralt M, Romeu M, Gonzalez S, Mallo J (2008) Polypodium leucotomos extract inhibits glutathione oxidation and prevents Langerhans cell depletion induced by UVB/UVA radiation in a hairless rat model. Exp Dermatol 17:653–658

(8)Philips N, Smith J, Se´ller T, Gonzalez S (2003) Predominant effect of Polypodium leucotomos on membrane integrity, lipid peroxidation expression of elastin and matrixmetalloproteinase-1 in ultraviolet radiation exposed fibroblasts, and keratinocytes. J Dermatol Sci 32:1–9

(9) Philips, N.; Conte, J.; Chen, Y.J.; Natrajan, P.; Taw, M.; Keller, T. Beneficial regulation of matrixmetalloproteinases and their inhibitors, fibrillar collagens and transforming growth factor-beta by Polypodium leucotomos, directly or in dermal fibroblasts, ultraviolet radiated fibroblasts, and melanoma cells. Arch. Dermatol. Res. 2009, 301, 487–495.